People with vitamin B12 deficiency can have neurological symptoms and/or damage without anemia (lack of red blood cells). General physical symptoms of vitamin B12 deficiency can include: Feeling very tired or weak. Experiencing nausea, vomiting or diarrhea. Not feeling as hungry as usual. Weight loss.. PMC7764703. 10.2147/TCRM.S274122. The neurotropic B vitamins B1 (thiamine), B6 (pyridoxine), and B12 (cobalamin) are essential for proper functioning of the nervous system. Deficiencies may induce neurological disorders like peripheral neuropathy (PN) and mainly occur in vulnerable populations (eg, elderly, diabetics, alcoholics).
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Vitamin B-6 (pyridoxine) is important for normal brain development and for keeping the nervous system and immune system healthy. Food sources of vitamin B-6 include poultry, fish, potatoes, chickpeas, bananas and fortified cereals. Vitamin B-6 can also be taken as a supplement, typically as an oral capsule, tablet or liquid.. Vitamin B-1 is administered in the form of a supplement or as a part of a multivitamin. Depending on the purpose, vitamin B-1 can be taken orally in pill form or as an injection. Vitamin B-12 is a readily consumable vitamin. It can be taken as a supplement or consumed in certain foods.